Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787200 | 0.94 | PTGS2 (0.31) | — | |
| SCHEMBL7804341 | 0.90 | CA2 (0.37) | MT-CO2TOP1 | |
| SCHEMBL7800486 | 0.89 | CA2 (0.37) | — | |
| SCHEMBL7802511 | 0.88 | AKR1C3 (0.30) | — | |
| SCHEMBL7784784 | 0.86 | MT-CO2 (0.39) | MT-CO2TOP1 | |
| SCHEMBL7803243 | 0.84 | MT-CO2 (0.36) | MT-CO2TOP1 | |
| SCHEMBL7787500 | 0.84 | MAPT (0.40) | — | |
| SCHEMBL7787570 | 0.83 | AKR1C3 (0.33) | — | |
| SCHEMBL7784773 | 0.80 | MAPT (0.36) | MT-CO2TOP1 | |
| SCHEMBL7794482 | 0.80 | CA2 (0.38) | MT-CO2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140291-A1 | COMBINATION CHEMOTHERAPY COMPRISING A MITOTIC INHIBITOR AND A MEK INHIBITOR | WARNER-LAMBERT COMPANY LLC (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037141-A9 | COMBINATION CHEMOTHERAPY | WARNER LAMBERT CO (US) | 2000-12-07 | — | — | WO | disclosed |
| WO-2000037141-A1 | COMBINATION CHEMOTHERAPY | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |