SCHEMBL7784928

SCHEMBL7784928

FC(F)(F)c1ccc(-c2ccc(Cl)cc2)[nH]1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.50
ALDH1A1 P00352 5/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.42
GLA P06280 1/20 0.42
CRHBP P24387 1/20 0.42
HTT P42858 1/20 0.42
CRHR2 Q13324 1/20 0.42
MAPT P10636 4/20 0.42
HSD17B2 P37059 2/20 0.39
POLB P06746 2/20 0.39
RAB9A P51151 2/20 0.39
MKNK1 Q9BUB5 1/20 0.39
MKNK2 Q9HBH9 1/20 0.39
IDO1 P14902 1/20 0.39
PPARG P37231 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9015133 0.80 KDM4E (0.46) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL7214808 0.79 KDM4E (0.43) ALDH1A1KMT2AKDM4EHPGDGAA
SCHEMBL8662106 0.72 GCGR (0.46) GCGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL9254439 0.72 GCGR (0.46) GCGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL3294173 0.69 KDM4E (0.37) ALDH1A1MEN1KMT2AKDM4EHPGD
SCHEMBL9254319 0.69 GCGR (0.43) GCGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL9015117 0.69 GCGR (0.50) GCGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL8798565 0.69 KDM4E (0.43) GCGRALDH1A1MEN1KMT2AKDM4E
SCHEMBL28130668 0.69 HSD17B2 (0.35) KDM4EHSD17B2
SCHEMBL26586294 0.68 GCGR (0.42) GCGRALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110049674-A Biocidal microcapsules for biofouling control 格林塞尔研究有限公司 2019-07-23 CN disclosed
EP-0801058-B1 Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents AMERICAN CYANAMID CO (US) 2001-10-10 EP disclosed
US-5817691-A Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents AMERICAN CYANAMID COMPANY (US) 1998-10-06 US disclosed
US-5739155-A Haloalkylthio,-sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID CO. (US) 1998-04-14 US disclosed
EP-0801058-A1 Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents American Cyanamid Company (US) 1997-10-15 EP disclosed
EP-0549866-B1 Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents AMERICAN CYANAMID CO (US) 1997-08-13 EP disclosed
EP-0487870-B1 Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds AMERICAN CYANAMID CO (US) 1996-12-18 EP disclosed
US-5484807-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents BASF AKTIENGESELLSCHAFT 1996-01-16 US disclosed
US-5468877-A FOR PROTECTING CROPS AMERICAN CYANAMID COMPANY (US) 1995-11-21 US disclosed
US-5306827-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal and acaricidal agents AMERICAN CYANAMID COMPANY (US) 1994-04-26 US disclosed
US-5284863-A Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole fungicidal agents AMERICAN CYANAMID COMPANY (US) 1994-02-08 US disclosed
EP-0549866-A1 Haloalkylthio, -sulfinyl and -sulfonyl arylpyrrole insecticidal, acaricidal and fungicidal agents AMERICAN CYANAMID COMPANY (US) 1993-07-07 EP disclosed