Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13417158 | 0.82 | HPGD (0.47) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL7784928 | 0.80 | GCGR (0.50) | KDM4EHPGDALDH1A1GAAGLA | |
| SCHEMBL7214808 | 0.79 | KDM4E (0.43) | KDM4EHPGDHSD17B10ALDH1A1GAA | |
| SCHEMBL6309866 | 0.78 | HPGD (0.59) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL12918686 | 0.72 | HPGD (0.53) | KDM4EHPGDUSP2HSD17B10ALDH1A1 | |
| SCHEMBL3294173 | 0.69 | KDM4E (0.37) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL22315193 | 0.69 | HMBS (0.50) | KDM4EHPGDMAPTHSD17B2 | |
| SCHEMBL17868402 | 0.68 | DGAT1 (0.53) | NPBWR1 | |
| SCHEMBL5352040 | 0.68 | SMN1; SMN2 (0.56) | KDM4EHPGDALDH1A1GAAGLA | |
| SCHEMBL10222198 | 0.68 | SCN2A (0.44) | CCNB2CDK1CCNB1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | claimed |
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | disclosed |
| EP-0487870-A2 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1992-06-03 | — | — | EP | disclosed |