Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785476 | 0.80 | MAPT (0.45) | ALPLGLAALPIALPGALDH1A1 | |
| SCHEMBL7780316 | 0.78 | ACP3 (0.49) | ALDH1A1GAALMNACYP3A4TDP1 | |
| SCHEMBL7787942 | 0.77 | TDP1 (0.49) | ALDH1A1GAALMNACYP3A4TDP1 | |
| SCHEMBL7785051 | 0.75 | ALPL (0.43) | ALPLGLAALPIALPGALDH1A1 | |
| SCHEMBL7780342 | 0.75 | KMT2A (0.54) | ALPLALDH1A1LMNATDP1KMT2A | |
| SCHEMBL7780357 | 0.75 | TDP1 (0.47) | ALDH1A1GAALMNACYP3A4TDP1 | |
| SCHEMBL7785233 | 0.75 | AOC3 (0.52) | ALDH1A1GAALMNATDP1KMT2A | |
| SCHEMBL7784989 | 0.75 | ACP3 (0.45) | ALDH1A1GAALMNACYP3A4TDP1 | |
| SCHEMBL7785046 | 0.74 | TDP1 (0.49) | ALDH1A1GAATDP1KMT2AMEN1 | |
| SCHEMBL7787522 | 0.74 | POLB (0.44) | ALDH1A1GAALMNATDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |