Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CASR | P41180 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787942 | 0.90 | TDP1 (0.49) | TDP1KMT2AMEN1PKMAOC3 | |
| SCHEMBL7785233 | 0.88 | AOC3 (0.52) | TDP1KMT2AMEN1AOC3ALDH1A1 | |
| SCHEMBL7780342 | 0.82 | KMT2A (0.54) | TDP1KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL7785046 | 0.81 | TDP1 (0.49) | TDP1KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL7780316 | 0.81 | ACP3 (0.49) | TDP1KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL7780340 | 0.80 | KMT2A (0.42) | TDP1KMT2AMEN1PKMALDH1A1 | |
| SCHEMBL7789152 | 0.80 | SIGMAR1 (0.53) | TDP1KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL7784989 | 0.78 | ACP3 (0.45) | TDP1KMT2AMEN1PKMAOC3 | |
| SCHEMBL7780362 | 0.77 | TDP1 (0.50) | TDP1KMT2AMEN1ALDH1A1CASR | |
| SCHEMBL7787461 | 0.76 | TDP1 (0.55) | TDP1KMT2AMEN1ALDH1A1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |