Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | CASR | P41180 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787942 | 0.87 | TDP1 (0.49) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL7785046 | 0.86 | TDP1 (0.49) | KMT2AHTTALDH1A1MEN1TDP1 | |
| SCHEMBL7789152 | 0.84 | SIGMAR1 (0.53) | KMT2AALDH1A1LMNAMEN1TDP1 | |
| SCHEMBL7785233 | 0.82 | AOC3 (0.52) | KMT2AALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7780357 | 0.82 | TDP1 (0.47) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL7785547 | 0.80 | SLC6A4 (0.42) | KMT2AHTTLMNAMEN1TDP1 | |
| SCHEMBL7785650 | 0.80 | KMT2A (0.50) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL7785298 | 0.80 | KMT2A (0.44) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL4228575 | 0.79 | MTOR (0.67) | KMT2AHTTALDH1A1LMNAMAPT | |
| SCHEMBL7789351 | 0.79 | TDP1 (0.41) | KMT2AHTTALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |