Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787942 | 0.90 | TDP1 (0.49) | AOC3ADRB3TDP1GAAKMT2A | |
| SCHEMBL7780357 | 0.88 | TDP1 (0.47) | AOC3ADRB3TDP1GAAKMT2A | |
| SCHEMBL7780342 | 0.82 | KMT2A (0.54) | TDP1SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7787584 | 0.82 | MEN1 (0.49) | ADRB3TDP1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7785046 | 0.81 | TDP1 (0.49) | TDP1GAAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7785275 | 0.81 | ADRB3 (0.46) | AOC3ADRB3TDP1GAAKDM4E | |
| SCHEMBL7789152 | 0.80 | SIGMAR1 (0.53) | TDP1GAAKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7780316 | 0.78 | ACP3 (0.49) | TDP1GAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL7785160 | 0.78 | ADRB3 (0.46) | AOC3ADRB3TDP1GAAKDM4E | |
| Hydrochloric Acid SCHEMBL7787644 | 0.76 | ALDH1A1 (0.67) | GAAKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |