Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785286 | 0.92 | LMNA (0.35) | SLC6A2SLC6A4LMNAALDH1A1MAPKAPK2 | |
| SCHEMBL7787788 | 0.92 | CASR (0.37) | CASRSLC6A2SLC6A4MAPK1LMNA | |
| SCHEMBL7780426 | 0.91 | SLC6A2 (0.41) | CASRSLC6A2SLC6A4MAPK1LMNA | |
| SCHEMBL28746788 | 0.91 | SLC6A2 (0.41) | CASRSLC6A2SLC6A4MAPK1LMNA | |
| SCHEMBL7780705 | 0.88 | LMNA (0.34) | SLC6A2SLC6A4MAPK1LMNAALDH1A1 | |
| SCHEMBL7785653 | 0.88 | SLC6A2 (0.36) | CASRSLC6A2SLC6A4 | |
| SCHEMBL7785553 | 0.88 | LMNA (0.34) | SLC6A2SLC6A4MAPK1LMNAALDH1A1 | |
| SCHEMBL7785107 | 0.86 | ALDH1A1 (0.50) | CASRLMNAALDH1A1GAAKRAS | |
| SCHEMBL27530316 | 0.86 | ALDH1A1 (0.50) | CASRLMNAALDH1A1GAAKRAS | |
| SCHEMBL7780790 | 0.86 | ALDH1A1 (0.50) | CASRLMNAALDH1A1GAAKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |