Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.34 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780321 | 0.91 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7785574 | 0.88 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7785129 | 0.88 | ALDH1A1 (0.45) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7787615 | 0.86 | MAPKAPK2 (0.33) | CYP3A4KRASSOS1SLC6A9SLC6A5 | |
| SCHEMBL27530316 | 0.85 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7780790 | 0.85 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7785107 | 0.85 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7785680 | 0.84 | NPC1 (0.41) | KMT2AALDH1A1LMNAGAAHTT | |
| SCHEMBL7784989 | 0.84 | ACP3 (0.45) | KMT2AMEN1ALDH1A1LMNAGAA | |
| SCHEMBL7780717 | 0.84 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |