Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729700 | 0.85 | CHRNB2 (0.51) | APPCHRNB2CHRNA4ADRB3CHRNB4 | |
| SCHEMBL7396426 | 0.82 | SMN1; SMN2 (0.53) | APPCHRNB2CHRNA4ADRB3TSHR | |
| SCHEMBL7510305 | 0.81 | LMNA (0.63) | APPCHRNB2CHRNA4ADRB3CHRNB4 | |
| SCHEMBL2059732 | 0.80 | TSHR (0.68) | APPCHRNB2CHRNA4ADRB3TSHR | |
| SCHEMBL3164505 | 0.79 | CHRNB2 (0.54) | APPCHRNB2CHRNA4ADRB3CHRNB4 | |
| SCHEMBL1369854 | 0.78 | LMNA (0.63) | ADRB3TSHRHIF1ASMN1; SMN2 | |
| SCHEMBL22207338 | 0.77 | ADRB3 (0.55) | APPCHRNB2CHRNA4ADRB3TSHR | |
| SCHEMBL5150482 | 0.76 | DRD2 (0.49) | APPCHRNB2CHRNA4ADRB3CHRNB4 | |
| SCHEMBL3788266 | 0.76 | CHRNB2 (0.55) | APPCHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL456312 | 0.76 | APP (0.50) | APPTSHRMAPK1HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853471-B1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | OREAL (FR) | 2001-10-31 | — | — | EP | claimed |
| US-6004356-A | HAIR DYES | L'OREAL (FR) | 1999-12-21 | — | — | US | claimed |
| EP-0853471-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-07-22 | — | — | EP | claimed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | claimed |
| WO-1997011674-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1997-04-03 | — | — | WO | claimed |
| EP-0728465-B1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | OREAL (FR) | 1997-03-19 | — | — | EP | claimed |
| EP-0728465-A1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0853471-B1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | OREAL (FR) | 2001-10-31 | — | — | EP | disclosed |
| US-6004356-A | HAIR DYES | L'OREAL (FR) | 1999-12-21 | — | — | US | disclosed |
| EP-0853471-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1998-07-22 | — | — | EP | disclosed |
| US-5735909-A | Compositions and processes for the oxidation dyeing of keratin fibres with an oxidation base, a meta-aminophenol coupler, and a 6-hydroxyindoline coupler | L'OREAL (FR) | 1998-04-07 | — | — | US | disclosed |
| WO-1997011674-A1 | COMPOSITION FOR OXIDATION DYEING KERATIN FIBRES, AND DYEING METHOD USING SAME | L'OREAL (FR) | 1997-04-03 | — | — | WO | disclosed |
| EP-0728465-B1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | OREAL (FR) | 1997-03-19 | — | — | EP | disclosed |
| EP-0728465-A1 | Composition for dyeing keratinous fibers comprising a meta-aminophenol and 6-hydroxyindoline, and dyeing process using such a composition | L'OREAL (FR) | 1996-08-28 | — | — | EP | disclosed |