Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378545 | 0.84 | PYCR1 (0.46) | ALDH1A1POLBMAPTGAAKCNH2 | |
| SCHEMBL7081483 | 0.80 | APP (0.50) | APPKCNH2 | |
| SCHEMBL4508653 | 0.78 | APP (0.58) | ALDH1A1LMNAPOLBMAPTNPC1 | |
| SCHEMBL7080591 | 0.77 | CYP2A6 (0.49) | ALDH1A1CYP19A1KCNH2 | |
| SCHEMBL27214761 | 0.73 | KCNJ1 (0.55) | ALDH1A1LMNAMAPTNPC1PKM | |
| SCHEMBL3128583 | 0.72 | HSPB1 (0.59) | ALDH1A1LMNAPOLBMAPTNPC1 | |
| Nitrogen SCHEMBL9082924 | 0.72 | APP (0.66) | ALDH1A1LMNAPOLBMAPTNPC1 | |
| SCHEMBL57257 | 0.72 | VCAM1 (0.61) | ALDH1A1LMNAMAPTNPC1PKM | |
| SCHEMBL492221 | 0.72 | APP (0.70) | ALDH1A1LMNAPOLBMAPTNPC1 | |
| SCHEMBL20328414 | 0.72 | APP (0.70) | ALDH1A1LMNAPOLBMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |