SCHEMBL890370

SCHEMBL890370

O=C(Cl)C1CCCC(C(=O)Cl)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
CHRNB2 P17787 2/20 0.38
CHRNA3 P32297 2/20 0.38
CHRNA4 P43681 2/20 0.38
CHRNB3 Q05901 2/20 0.38
CHRNA6 Q15825 2/20 0.38
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NOS2 P35228 1/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
RECQL P46063 1/20 0.34
GAA P10253 2/20 0.32
RAB9A P51151 1/20 0.32
HSD11B1 P28845 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16941963 1.00 CES2 (0.43) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL21391822 0.90 CES2 (0.45) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL126540 0.90
SCHEMBL21391916 0.88 CES2 (0.50) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL21391917 0.88 CES2 (0.43) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL14273180 0.88 CES2 (0.50) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL2154406 0.87 ACE (0.36) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL21391824 0.85 CES2 (0.55) CES2CES1CHRNB2CHRNA3CHRNA4
SCHEMBL101983 0.84
SCHEMBL13397790 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3412732-B1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEMICAL LTD (KR) 2025-02-19 EP claimed
CN-118142347-A Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer 中国石油大学(华东) 2024-06-07 CN claimed
US-10717819-B2 Polyimide-based block copolymer film LG CHEM, LTD. (KR) 2020-07-21 US claimed
US-20190153159-A1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEM, LTD. (KR) 2019-05-23 US claimed
EP-3412732-A1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG Chem, Ltd. (KR) 2018-12-12 EP claimed
EP-1149836-B1 Polynalbuphine derivatives HU OLIVER YOA PU (TW) 2003-02-26 EP claimed
EP-1149836-A1 Polynalbuphine derivatives Hu, Oliver Yoa-Pu (TW) 2001-10-31 EP claimed
EP-3486271-B1 POLYIMIDE-BASED BLOCK COPOLYMER AND POLYIMIDE-BASED FILM COMPRISING SAME LG CHEMICAL LTD (KR) 2025-02-19 EP disclosed
EP-3412732-B1 POLYIMIDE-BASED BLOCK COPOLYMER FILM LG CHEMICAL LTD (KR) 2025-02-19 EP disclosed
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME THE PENN STATE RESEARCH FOUNDATION 2024-10-10 US disclosed
US-12036515-B2 Thin-film composite membrane and methods of making and using the same THE PENN STATE RESEARCH FOUNDATION (PA) 2024-07-16 US disclosed
CN-118142347-A Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer 中国石油大学(华东) 2024-06-07 CN disclosed
US-20240101751-A1 HOLLOW MICROBALLOON TOKUYAMA CORPORATION (JP) 2024-03-28 US disclosed
US-4310652-A Melt processable poly(ester carbonate) with high glass transition temperature ALLIED CHEMICAL CORPORATION (US) 1982-01-12 US disclosed
EP-0036629-A1 Melt processable poly(ester carbonate) with high glass transition temperature ALLIED CORPORATION (US) 1981-09-30 EP disclosed
EP-0027844-A1 Poly(ester carbonate) with high glass transition temperature ALLIED CORPORATION (US) 1981-05-06 EP disclosed
US-4255556-A Preparation of poly(ester carbonate) by interfacial method ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
EP-0017740-A1 Preparation of poly(ester carbonate) by interfacial method ALLIED CORPORATION (US) 1980-10-29 EP disclosed
US-4214071-A Amide-imide polymers WESTINGHOUSE ELECTRIC CORP. (US) 1980-07-22 US disclosed
US-4059565-A Process for producing a branched polycarbonate or poly(ester-carbonate) MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335796-A1 THIN-FILM COMPOSITE MEMBRANE AND METHODS OF MAKING AND USING THE SAME PORCN, MLEC, FLOT1 CES2 3160/4885CES1 4054/4885CHRNB2 4601/4885
US-12036515-B2 Thin-film composite membrane and methods of making and using the same PORCN, MLEC, FLOT1 CES2 3160/4885CES1 4054/4885CHRNB2 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.