SCHEMBL7787236

SCHEMBL7787236

CCCCOC(=O)CC(=O)c1cc(C)c(C)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TSHR P16473 2/20 0.41
NPC1 O15118 1/20 0.40
HPGD P15428 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FAAH O00519 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NAAA Q02083 1/20 0.38
ALDH1A1 P00352 2/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7789467 0.96 FAAH (0.44) ESR1TSHRFAAHNAAAALDH1A1
SCHEMBL7787210 0.94 FAAH (0.47) ESR1TSHRFAAHNAAAALDH1A1
SCHEMBL7789518 0.91 ALDH1A1 (0.39) TDP1HPGDSMN1; SMN2MEN1KMT2A
SCHEMBL7787218 0.86 MGAM (0.47) TSHRHPGDSMN1; SMN2MEN1KMT2A
SCHEMBL7787256 0.79 KMT2A (0.37) L3MBTL1TSHRNPC1RAB9AMEN1
SCHEMBL9278783 0.72 MAPT (0.38) L3MBTL1NPC1RAB9AMEN1KMT2A
SCHEMBL9745314 0.71 HTT (0.58) ESR1CYP1A2CYP2C9CYP2C19TDP1
SCHEMBL152233 0.71 ALDH1A1 (0.61) TSHRHPGDFAAHNAAAALDH1A1
SCHEMBL4627375 0.71 TSHR (0.65) ESR1CYP1A2CYP2C19TDP1L3MBTL1
SCHEMBL7786525 0.70 GAA (0.47) TDP1TSHRSMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746306-B1 BENZOYLACETATE ESTERS AS NON-SENSITIZING CHELATING PHOTO-PROTECTANTS PROCTER & GAMBLE (US) 2001-11-07 EP disclosed
US-5492690-A ABSORB ULTRAVIOLET LIGHT, CHELATE METALS TO INHIBIT FORMATION OF FREE RADICALS THE PROCTER & GAMBLE COMPANY (US) 1996-02-20 US disclosed