Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787210 | 0.99 | FAAH (0.47) | FAAHNAAAESR1TSHRTP53 | |
| SCHEMBL7787236 | 0.96 | ESR1 (0.43) | FAAHNAAAESR1TSHRTP53 | |
| SCHEMBL7789518 | 0.90 | ALDH1A1 (0.39) | MAPK1ALDH1A1LMNA | |
| SCHEMBL7787218 | 0.85 | MGAM (0.47) | TSHRALDH1A1 | |
| SCHEMBL7787256 | 0.78 | KMT2A (0.37) | TSHRALDH1A1LMNA | |
| SCHEMBL28785734 | 0.72 | ESR1 (0.77) | ESR1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL240774 | 0.72 | NAAA (0.71) | FAAHNAAATSHRALDH1A1RAD52 | |
| SCHEMBL29404235 | 0.72 | TSHR (0.66) | ESR1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL28367461 | 0.72 | TSHR (0.66) | ESR1TSHRTP53CYP3A4MAPK1 | |
| SCHEMBL9278783 | 0.71 | MAPT (0.38) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746306-B1 | BENZOYLACETATE ESTERS AS NON-SENSITIZING CHELATING PHOTO-PROTECTANTS | PROCTER & GAMBLE (US) | 2001-11-07 | — | — | EP | disclosed |
| US-5492690-A | ABSORB ULTRAVIOLET LIGHT, CHELATE METALS TO INHIBIT FORMATION OF FREE RADICALS | THE PROCTER & GAMBLE COMPANY (US) | 1996-02-20 | — | — | US | disclosed |