Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | EEF2K | O00418 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786042 | 0.77 | MDM2 (0.39) | PDE2ACYP2D6KCNH2 | |
| SCHEMBL18075371 | 0.77 | PDE2A (1.00) | PDE2ACYP2D6CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL18255072 | 0.77 | PDE2A (0.55) | PDE2ACYP2D6CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL30514270 | 0.77 | ADRA2C (0.50) | KCNH2LMNAMAPT | |
| SCHEMBL7786053 | 0.77 | ADRA2C (0.50) | KCNH2LMNAMAPT | |
| SCHEMBL7455141 | 0.77 | ADRA2C (0.50) | KCNH2LMNAMAPT | |
| SCHEMBL1350263 | 0.75 | PDE2A (0.69) | PDE2ACYP2D6CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL7783863 | 0.75 | TSHR (0.36) | PDE2ALMNAALDH1A1MAPT | |
| SCHEMBL6644323 | 0.74 | PDE2A (0.65) | PDE2ACYP2D6CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL7787266 | 0.74 | LMNA (0.37) | PDE2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |