Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360226 | 1.00 | LMNA (0.44) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL5057122 | 1.00 | LMNA (0.44) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL7783897 | 0.88 | ADRA1A (0.42) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL5057097 | 0.88 | ADRA1A (0.42) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| Hydrochloric Acid SCHEMBL8781949 | 0.86 | BLM (0.44) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL6055257 | 0.83 | TRPA1 (0.47) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL14168846 | 0.83 | LMNA (0.45) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL14168844 | 0.83 | LMNA (0.45) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL6392204 | 0.83 | LMNA (0.45) | LMNAADRA1AHTR2BTRPA1CHRM1 | |
| SCHEMBL6814024 | 0.82 | ADRA1A (0.50) | LMNAADRA1AHTR2BADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |