Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7783897 | 1.00 | ADRA1A (0.42) | ADRA1AADRA2ACYP2D6BLMKMT2A | |
| Hydrochloric Acid SCHEMBL8781949 | 0.98 | BLM (0.44) | ADRA1AADRA2ACYP2D6BLMKMT2A | |
| SCHEMBL7787261 | 0.88 | LMNA (0.44) | ADRA1AADRA2ACYP2D6BLMKMT2A | |
| SCHEMBL21360226 | 0.88 | LMNA (0.44) | ADRA1AADRA2ACYP2D6BLMKMT2A | |
| SCHEMBL5057122 | 0.88 | LMNA (0.44) | ADRA1AADRA2ACYP2D6BLMKMT2A | |
| SCHEMBL4169342 | 0.83 | LMNA (0.42) | ADRA1AKMT2AMEN1LMNATDP1 | |
| SCHEMBL4178220 | 0.83 | LMNA (0.42) | ADRA1AKMT2AMEN1LMNATDP1 | |
| SCHEMBL4161041 | 0.83 | LMNA (0.42) | ADRA1AKMT2AMEN1LMNATDP1 | |
| SCHEMBL9984624 | 0.83 | ALDH1A1 (0.46) | ADRA1ACYP2D6KMT2AMEN1KDM4E | |
| SCHEMBL8285908 | 0.83 | ALDH1A1 (0.46) | ADRA1ACYP2D6KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713848-B1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY (JP) | 1999-09-08 | — | — | EP | claimed |
| US-5831132-A | REDUCING AGENT FROM BORANES AND AMINO ALCOHOLS | SUMIKA FINE CHEMICALS COMPANY, LTD. (JP) | 1998-11-03 | — | — | US | claimed |
| EP-0713848-A1 | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1996-05-29 | — | — | EP | claimed |
| JP-61078754-A | — | — | None | — | — | JP | disclosed |
| US-7365212-B2 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | ZACH SYSTEM S.P.A. (IT) | 2008-04-29 | — | — | US | disclosed |
| EP-1673375-B1 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG SIPSY (FR) | 2007-08-01 | — | — | EP | disclosed |
| US-20070055068-A1 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | PPG-SIPSY (FR) | 2007-03-08 | — | — | US | disclosed |
| EP-1673375-A2 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG-Sipsy (FR) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005035540-A2 | METHOD FOR THE IN SITU PREPARATION OF CHIRAL COMPOUNDS DERIVED FROM OXAZABOROLIDINE-BORANE COMPLEXES, WHICH ARE USED IN ASYMMETRIC REDUCTION REACTIONS | PPG-SIPSY (FR) | 2005-04-21 | — | — | WO | disclosed |
| EP-0736509-B1 | Processes for preparing optically active alcohols and optically active amines | SUMITOMO CHEMICAL CO (JP) | 2001-11-14 | — | — | EP | disclosed |
| US-6156940-A | Process for producing optically active carbinols | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 2000-12-05 | — | — | US | disclosed |
| US-4923999-A | Optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-05-08 | — | — | US | disclosed |
| EP-0142566-B1 | ASYMMETRICALLY MODIFIED BORON HYDRIDE COMPOUNDS, PROCESS FOR ITS PREPARATION, AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOL DERIVATIVE USING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0171175-B1 | AN OPTICALLY ACTIVE BORANE COMPLEX AND A METHOD FOR PRODUCING AN OPTICALLY ACTIVE ALCOHOL DERIVATIVE BY THE USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-24 | — | — | EP | disclosed |
| US-4760149-A | Asymmetrically reducing a ketone with an asymmetrically modified borohydride compound obtained by reacting a borohydride with optically active amino alcohol | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-26 | — | — | US | disclosed |
| US-4749809-A | Optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-06-07 | — | — | US | disclosed |
| EP-0237305-A2 | A method for producing optically active amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-09-16 | — | — | EP | disclosed |
| JP-S6178754-A | AMINOALCOHOL AND ITS PREPARATION | SUMITOMO CHEM CO LTD | 1986-04-22 | — | — | JP | disclosed |
| EP-0171175-A1 | An optically active borane complex and a method for producing an optically active alcohol derivative by the use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-02-12 | — | — | EP | disclosed |
| EP-0142566-A1 | ASYMMETRICALLY MODIFIED BORON HYDRIDE COMPOUNDS, PROCESS FOR ITS PREPARATION, AND PROCESS FOR PREPARING OPTICALLY ACTIVE ALCOHOL DERIVATIVE USING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-05-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070055068-A1 | Method for the in situ preparation of chiral compounds derived from oxazaborolidine-borane complexes which are used in asymmetric reduction reactions | OGFR, OXSR1, OTC | ADRA1A 1001/4885ADRA2A 917/4885CYP2D6 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.