Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 7/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.46 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL887094 | 0.99 | P2RX3 (0.50) | P2RX3P2RX1P2RX2GPR17P2RX4 | |
| SCHEMBL4745859 | 0.92 | DNPH1 (0.48) | POLBP2RY1P2RY2SRCALDH1A1 | |
| Didanosine SCHEMBL6066346 | 0.90 | ALDH1A1 (0.53) | P2RX3P2RX1P2RX2GPR17P2RX4 | |
| SCHEMBL23978230 | 0.89 | P2RX3 (0.61) | P2RX3P2RX1P2RX2P2RX4POLB | |
| SCHEMBL4969963 | 0.89 | P2RX3 (0.61) | P2RX3P2RX1P2RX2P2RX4POLB | |
| SCHEMBL31229395 | 0.89 | P2RX3 (0.61) | P2RX3P2RX1P2RX2P2RX4POLB | |
| SCHEMBL13604126 | 0.88 | P2RX3 (0.49) | P2RX3P2RX1P2RX2GPR17P2RX4 | |
| Dda-Triphosphate SCHEMBL23978346 | 0.88 | P2RX3 (0.63) | P2RX3P2RX1P2RX2P2RX4POLB | |
| SCHEMBL8630966 | 0.88 | P2RX3 (0.63) | P2RX3P2RX1P2RX2P2RX4POLB | |
| Dda-Triphosphate SCHEMBL12932305 | 0.88 | P2RX3 (0.63) | P2RX3P2RX1P2RX2P2RX4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252060-B1 | COMPLEX CONTAINING DIDEOXYGUANOSINE | NEXSTAR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |
| US-5817638-A | USING HYBRID NUCLEOSIDES | NEXSTAR PHARMACEUTICALS, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0594677-A4 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL INC (US) | 1997-09-17 | — | — | EP | disclosed |
| EP-0594677-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | NeXstar Pharmaceuticals, Inc. (US) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993000910-A1 | ANTIVIRAL LIPONUCLEOSIDES: TREATMENT OF HEPATITIS B | VICAL, INC. (US) | 1993-01-21 | — | — | WO | disclosed |