Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188707 | 0.95 | TSHR (0.63) | TSHRALDH1A1MAPTKMT2ACYP3A4 | |
| SCHEMBL1641682 | 0.90 | CHRNB2 (0.65) | TSHRALDH1A1CYP3A4TP53KDM4E | |
| Hydrochloric Acid SCHEMBL310652 | 0.88 | CHRNB2 (0.63) | TSHRALDH1A1CYP3A4TP53KDM4E | |
| Hydrochloric Acid SCHEMBL309555 | 0.88 | CHRNB2 (0.63) | TSHRALDH1A1CYP3A4TP53KDM4E | |
| SCHEMBL29437009 | 0.86 | TSHR (0.79) | TSHRALDH1A1CYP3A4TP53MAOB | |
| SCHEMBL441825 | 0.86 | TSHR (0.79) | TSHRALDH1A1CYP3A4TP53MAOB | |
| SCHEMBL18045584 | 0.84 | TSHR (0.82) | TSHRALDH1A1CYP3A4TP53MAOB | |
| SCHEMBL18045565 | 0.84 | TSHR (0.82) | TSHRALDH1A1CYP3A4TP53MAOB | |
| SCHEMBL5069212 | 0.84 | TSHR (0.82) | TSHRALDH1A1CYP3A4TP53MAOB | |
| SCHEMBL18045545 | 0.84 | TSHR (0.82) | TSHRALDH1A1CYP3A4TP53MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010014691-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | TARGACEPT, INC. | 2001-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014691-A1 | PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE | PNMT, HNMT, CHRM3 | TSHR 952/4885ALDH1A1 3285/4885MAPT 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.