Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 3/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 3/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 3/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 3/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 3/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 3/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 3/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 3/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3727195 | 0.95 | CTSD (0.53) | CTSDATMF2CTSKCTSL | |
| SCHEMBL7791929 | 0.91 | CTSD (0.44) | CTSDATMF2CTSKCTSL | |
| SCHEMBL7791933 | 0.90 | CTSD (0.49) | CTSDATMF2CTSKCTSL | |
| SCHEMBL3734188 | 0.89 | FFAR4 (0.49) | CTSDCTSKCTSLCTSSMEN1 | |
| SCHEMBL3727193 | 0.88 | CTSD (0.49) | CTSDATMF2CTSKCTSL | |
| SCHEMBL7790683 | 0.82 | CASP1 (0.46) | CTSDCTSKCTSLCTSSMEN1 | |
| SCHEMBL3728055 | 0.80 | CTSL (0.53) | CTSKCTSLCTSSECE1MME | |
| SCHEMBL3740295 | 0.79 | CASP1 (0.46) | CTSDCTSKCTSLCTSSMEN1 | |
| SCHEMBL7787410 | 0.77 | CASP1 (0.44) | CTSDCTSKCTSLCTSSMEN1 | |
| SCHEMBL3732276 | 0.74 | ATM (0.51) | CTSDATMCTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150956-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047561-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | MEDIVIR AB (SE) | 2000-08-17 | — | — | WO | disclosed |