Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.72 |
| ▸ | HTR2C | P28335 | 4/20 | 0.72 |
| ▸ | HTR2B | P41595 | 3/20 | 0.72 |
| ▸ | DRD2 | P14416 | 4/20 | 0.63 |
| ▸ | HTR1A | P08908 | 3/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | DRD5 | P21918 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5183977 | 0.84 | MEN1 (0.60) | HTR2AHTR2CHTR2BHTR7ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5987883 | 0.82 | ALDH1A1 (0.58) | HTR2AHTR2CHTR2BHTR7ALDH1A1 | |
| SCHEMBL9633099 | 0.78 | HTR1A (0.75) | HTR2AHTR2BDRD2HTR1ADRD3 | |
| SCHEMBL9143897 | 0.77 | DRD2 (0.49) | HTR2AHTR2CHTR2BDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL10423847 | 0.76 | HTR1A (0.64) | HTR2AHTR2CDRD2HTR1ADRD3 | |
| SCHEMBL27236994 | 0.76 | HTR1A (1.00) | HTR2AHTR2CHTR2BDRD2HTR1A | |
| Hydrochloric Acid SCHEMBL7250731 | 0.75 | OGA (0.51) | ALDH1A1MDM2CA1CA2CA7 | |
| SCHEMBL10332949 | 0.75 | HRH3 (0.62) | HTR2AHTR2CDRD2HTR1ADRD3 | |
| SCHEMBL9143760 | 0.75 | HTR2A (1.00) | HTR2AHTR2CHTR2BDRD2HTR1A | |
| SCHEMBL9140144 | 0.75 | DRD2 (0.53) | HTR2AHTR2CDRD2HTR1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001072660-A | TNF-α PRODUCTION INHIBITOR AND/OR IL-10 PRODUCTION PROMOTER | WELFIDE CORP | 2001-03-21 | — | — | JP | disclosed |