Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 5/20 | 0.43 |
| ▸ | RXRB | P28702 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 7/20 | 0.37 |
| ▸ | RARG | P13631 | 7/20 | 0.37 |
| ▸ | RARA | P10276 | 5/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912346 | 0.87 | ABCB11 (0.39) | ABCB11RXRARXRBCYP26A1CYP3A4 | |
| SCHEMBL7787538 | 0.86 | ABCB11 (0.41) | ABCB11RXRARXRBCYP26A1CYP3A4 | |
| SCHEMBL11215262 | 0.80 | RXRA (0.46) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL11227826 | 0.77 | RXRA (0.43) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| Bromide SCHEMBL9159462 | 0.75 | RXRA (0.42) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL8824861 | 0.75 | ABCB11 (0.41) | ABCB11RXRARXRBKARS1USP2 | |
| SCHEMBL7782012 | 0.75 | ABCB11 (0.41) | ABCB11RXRARXRBKARS1USP2 | |
| SCHEMBL2641075 | 0.70 | ABCB11 (0.52) | ABCB11 | |
| SCHEMBL3541162 | 0.69 | RXRA (0.58) | RXRARXRBCYP26A1CYP3A4CYP26B1 | |
| SCHEMBL8736104 | 0.69 | RXRA (0.50) | RXRARXRBCYP26A1CYP3A4CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842928-B1 | PROCESS FOR PRODUCING ISOCHROMAN COMPOUNDS | KAO CORP (JP) | 2001-10-24 | — | — | EP | disclosed |
| EP-0842928-A1 | PROCESS FOR PRODUCING ISOCHROMAN COMPOUNDS | Kao Corporation (JP) | 1998-05-20 | — | — | EP | disclosed |