SCHEMBL7787607

SCHEMBL7787607

Cc1ccc([N]C(=O)N(c2ccccc2)N(C(=O)Nc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HPGD P15428 4/20 0.43
SMN1; SMN2 Q16637 6/20 0.41
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
MAPT P10636 4/20 0.41
TP53 P04637 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 1/20 0.39
CCR6 P51684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.38
MTOR P42345 1/20 0.38
USP2 O75604 1/20 0.37
GAA P10253 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30879612 0.79 MEN1 (0.59) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL77002 0.75 SMN1; SMN2 (0.51) MEN1KMT2AHPGDSMN1; SMN2NPC1
SCHEMBL28437969 0.70 RAB9A (0.57) MEN1KMT2AHPGDSMN1; SMN2NPC1
SCHEMBL17028035 0.69 KMT2A (0.53) MEN1KMT2AHPGDSMN1; SMN2NPC1
SCHEMBL8921448 0.69 RAB9A (0.53) MEN1KMT2AHPGDSMN1; SMN2NPC1
Fenuron SCHEMBL6304636 0.68 TSHR (0.56) MEN1KMT2AMTOR
SCHEMBL23289916 0.66 HPGD (0.47) MEN1KMT2AHPGDRAB9AMAPT
SCHEMBL11182821 0.66 TDP1 (0.55) SMN1; SMN2NPC1RAB9AMAPTALDH1A1
SCHEMBL2512409 0.66 MLYCD (0.65) MEN1KMT2ASMN1; SMN2NPC1RAB9A
SCHEMBL6682872 0.66 MEN1 (0.56) MEN1KMT2ASMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010010895-A1 COLOR PHOTOGRAPHIC ELEMENT CONTAINING NITROGEN HETEROCYCLE DERIVATIVE AND INHIBITOR RELEASING COUPLER CITICORP NORTH AMERICA, INC., AS AGENT 2001-08-02 US disclosed