SCHEMBL8921448

SCHEMBL8921448

[C]N(C(=O)Nc1ccccc1)c1ccc(C)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.53
NPC1 O15118 6/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
MAPT P10636 3/20 0.53
HPGD P15428 3/20 0.50
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
TP53 P04637 1/20 0.46
LMNA P02545 1/20 0.45
CCR6 P51684 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NOX1 Q9Y5S8 1/20 0.45
GAA P10253 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
NAPRT Q6XQN6 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenuron SCHEMBL6304636 0.75 TSHR (0.56) MEN1KMT2A
SCHEMBL28437969 0.75 RAB9A (0.57) RAB9ANPC1SMN1; SMN2MAPTHPGD
SCHEMBL13603928 0.73 KMT2A (0.57) RAB9ANPC1SMN1; SMN2MAPTHPGD
SCHEMBL178425 0.73 RAB9A (0.85) RAB9ANPC1SMN1; SMN2MAPTHPGD
SCHEMBL9547555 0.73 TDP1 (0.55) RAB9ANPC1SMN1; SMN2MAPTHPGD
SCHEMBL16518678 0.73 MLYCD (0.69) RAB9ANPC1SMN1; SMN2MAPTMEN1
SCHEMBL19216503 0.73 TDP1 (0.55) RAB9ANPC1SMN1; SMN2MAPTHPGD
SCHEMBL366747 0.72 SMN1; SMN2 (0.74) RAB9ANPC1SMN1; SMN2MAPTHPGD
Toluene SCHEMBL28333295 0.72 NAPRT (0.60) RAB9ANPC1SMN1; SMN2MAPTHPGD
Toluene SCHEMBL28033107 0.72 NAPRT (0.60) RAB9ANPC1SMN1; SMN2MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0715625-B1 WOOD PRESERVATIVE OXATHIAZINES UNIROYAL CHEM CO INC (US) 1997-06-04 EP claimed