Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD1 | P21728 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787622 | 0.92 | AKT1 (0.51) | AKT1RXRAESR1ESR2ALDH1A1 | |
| SCHEMBL3926924 | 0.84 | SIGMAR1 (0.47) | RXRASIGMAR1ALDH1A1TRPM8DRD2 | |
| SCHEMBL11705856 | 0.77 | AKT1 (0.55) | AKT1RXRAESR1ESR2ALDH1A1 | |
| SCHEMBL30009327 | 0.75 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1TRPM8DRD2HTR2A | |
| SCHEMBL4475359 | 0.75 | AKT1 (0.49) | AKT1ESR1ESR2ENTPD5EPHX2 | |
| SCHEMBL3184205 | 0.75 | AKT1 (0.56) | AKT1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL30513267 | 0.75 | AKT1 (0.56) | AKT1ESR1ESR2ALDH1A1MAPT | |
| SCHEMBL2348744 | 0.71 | AKT1 (0.46) | AKT1ESR1ESR2DRD2DRD1 | |
| SCHEMBL27703890 | 0.71 | SIGMAR1 (0.38) | AKT1ESR1ESR2SIGMAR1ALDH1A1 | |
| SCHEMBL9843380 | 0.71 | AKT1 (0.46) | AKT1RXRAESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276742-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, POLARIZING PLATE, IMAGE DISPLAY DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2019-09-12 | — | — | US | disclosed |