Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776683 | 0.95 | LMNA (0.45) | CA2LMNAMGLLPTPN2PTPN1 | |
| SCHEMBL778771 | 0.87 | LMNA (0.43) | CA2LMNAESR1ESR2SMN1; SMN2 | |
| SCHEMBL2484124 | 0.87 | CA2 (0.44) | CA2LMNAMGLLPTPN2PTPN1 | |
| SCHEMBL30446884 | 0.85 | CA2 (0.57) | CA2LMNAMGLLSMN1; SMN2TSHR | |
| SCHEMBL4333544 | 0.80 | CA2 (0.49) | CA2LMNAMGLLSMN1; SMN2TSHR | |
| SCHEMBL775809 | 0.78 | CA2 (0.47) | CA2LMNAMGLLSMN1; SMN2TSHR | |
| SCHEMBL21111342 | 0.78 | SMN1; SMN2 (0.58) | CA2SMN1; SMN2TSHRALDH1A1CYP2D6 | |
| SCHEMBL1806460 | 0.78 | CA2 (0.70) | CA2LMNAMGLLSMN1; SMN2TSHR | |
| SCHEMBL1806457 | 0.78 | CA2 (0.50) | CA2LMNAMGLLSMN1; SMN2TSHR | |
| SCHEMBL13303200 | 0.78 | CA2 (0.43) | CA2LMNAMGLLPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141915-A1 | METHOD FOR PREPARING IMIDAZOLE DERIVATIVE AND INTERMEDIATE THEREOF AND CRYSTAL FORM | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141915-A1 | METHOD FOR PREPARING IMIDAZOLE DERIVATIVE AND INTERMEDIATE THEREOF AND CRYSTAL FORM | CYP4B1, CYP2F1, CYP51A1 | CA2 4573/4885LMNA 921/4885MGLL 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.