Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787461 | 0.87 | TDP1 (0.55) | TDP1MEN1KMT2AL3MBTL1HTT | |
| SCHEMBL7780705 | 0.78 | LMNA (0.34) | SMN1; SMN2MEN1KMT2AHTTPGR | |
| SCHEMBL7785553 | 0.78 | LMNA (0.34) | SMN1; SMN2MEN1KMT2AHTTPGR | |
| SCHEMBL31067567 | 0.74 | L3MBTL1 (0.49) | TDP1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL17064881 | 0.74 | L3MBTL1 (0.49) | TDP1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL7780362 | 0.74 | TDP1 (0.50) | TDP1MEN1KMT2ARXRAHNF4A | |
| SCHEMBL15787159 | 0.72 | LMNA (0.42) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL15787623 | 0.72 | LMNA (0.42) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL23428905 | 0.71 | L3MBTL1 (0.49) | TDP1SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL4055615 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |