Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 4/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780362 | 0.87 | TDP1 (0.50) | TDP1CASRMEN1KMT2AALDH1A1 | |
| SCHEMBL7787859 | 0.87 | TDP1 (0.38) | TDP1MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL7784940 | 0.82 | TDP1 (0.50) | TDP1CASRMEN1KMT2AALDH1A1 | |
| SCHEMBL7780329 | 0.80 | ALDH1A1 (0.39) | TDP1CASRADRB2KMT2AL3MBTL1 | |
| SCHEMBL7785127 | 0.79 | ALDH1A1 (0.41) | TDP1CASRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7780432 | 0.79 | ALDH1A1 (0.41) | TDP1CASRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7780640 | 0.79 | ALDH1A1 (0.41) | TDP1CASRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7789351 | 0.77 | TDP1 (0.41) | TDP1CASRMEN1KMT2AL3MBTL1 | |
| SCHEMBL7803612 | 0.77 | TDP1 (0.45) | TDP1CASRMEN1KMT2AL3MBTL1 | |
| SCHEMBL28744674 | 0.76 | ALDH1A1 (0.39) | CASRL3MBTL1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |