Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 4/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787602 | 0.89 | ALDH1A1 (0.44) | TDP1ALDH1A1LMNAGAAMAOB | |
| SCHEMBL7787461 | 0.87 | TDP1 (0.55) | TDP1ALDH1A1LMNAGAACASR | |
| SCHEMBL7789351 | 0.83 | TDP1 (0.41) | TDP1ALDH1A1LMNAGAACASR | |
| SCHEMBL7780313 | 0.81 | TDP1 (0.41) | TDP1ALDH1A1LMNAGAACASR | |
| SCHEMBL7787614 | 0.80 | GAA (0.48) | TDP1ALDH1A1LMNAGAARXRA | |
| SCHEMBL7785107 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAGAACASRKMT2A | |
| SCHEMBL7785046 | 0.79 | TDP1 (0.49) | TDP1ALDH1A1GAACASRMEN1 | |
| SCHEMBL7780790 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAGAACASRKMT2A | |
| SCHEMBL27530316 | 0.79 | ALDH1A1 (0.50) | ALDH1A1LMNAGAACASRKMT2A | |
| SCHEMBL7780429 | 0.78 | TDP1 (0.42) | TDP1ALDH1A1LMNAGAACASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |