SCHEMBL7788640

SCHEMBL7788640

CNc1ccc(C)cc1.Cc1ccc(N)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.65
TEAD4 Q15561 1/20 0.50
MAPT P10636 7/20 0.48
TDP1 Q9NUW8 4/20 0.48
ALDH1A1 P00352 3/20 0.48
POLB P06746 2/20 0.48
GAA P10253 2/20 0.42
TSHR P16473 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
HTR6 P50406 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
HPGD P15428 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL525926 0.89
Hydrochloric Acid SCHEMBL1154858 0.87 TSHR (0.48) ACHEMAPTTDP1ALDH1A1TSHR
Hydrochloric Acid SCHEMBL6010014 0.87 TSHR (0.48) ACHEMAPTTDP1ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL11052046 0.87 TSHR (0.48) ACHEMAPTTDP1ALDH1A1POLB
SCHEMBL44533 0.87
SCHEMBL1389443 0.84 ALDH1A1 (0.52) ACHETEAD4MAPTTDP1ALDH1A1
Hydrochloric Acid SCHEMBL2866389 0.84 MAPT (0.50) ACHEMAPTTDP1ALDH1A1POLB
Dimethylamine SCHEMBL4362336 0.84 ACHE (0.81) ACHETEAD4MAPTTDP1ALDH1A1
SCHEMBL20048273 0.82 CYP3A4 (0.58) ACHEMAPTTDP1ALDH1A1TSHR
SCHEMBL22427634 0.82 MAPT (0.61) ACHEMAPTTDP1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200199485-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RES & ENG CO (US) 2020-06-25 US claimed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO claimed
US-12010990-B2 Hydrophobic polymers as oil rheology modifiers for agrochemical formulations DOW GLOBAL TECHNOLOGIES LLC (US) 2024-06-18 US disclosed
EP-3613832-B1 LUBRICATING GREASE OF POLYUREA/HIGH BASE NUMBER CALCIUM SULFONATE COMPOSITE LANXESS CORP (US) 2023-12-20 EP disclosed
WO-2023125235-A1 POLYUREA/CALCIUM SULFONATE COMPLEX GREASE COMPOSITION FOR USE IN CONSTANT VELOCITY JOINTS LANXESS SPECIALTY CHEMICALS CO., LTD. (CN) 2023-07-06 WO disclosed
US-11692151-B2 Lubricating grease of polyurea/high base number calcium sulfonate composite LANXESS CORPORATION (US) 2023-07-04 US disclosed
US-20220081639-A1 LUBRICATING GREASE OF POLYUREA/HIGH BASE NUMBER CALCIUM SULFONATE COMPOSITE LANXESS CORPORATION (US) 2022-03-17 US disclosed
US-11225627-B2 Lubricating grease of polyurea/high base number calcium sulfonate composite LANXESS CORPORATION (US) 2022-01-18 US disclosed
EP-3754002-A1 LUBRICATING GREASE OF POLYUREA/HIGH BASE NUMBER CALCIUM SULFONATE COMPOSITE Chemtura Chemicals (Nanjing) Company Limited (CN) 2020-12-23 EP disclosed
US-20200288704-A1 HYDROPHOBIC POLYMERS AS OIL RHEOLOGY MODIFIERS FOR AGROCHEMICAL FORMULATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-17 US disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
US-4929371-A Steel mill grease AMOCO CORPORATION (US) 1990-05-29 US disclosed
US-4904399-A USING SPECIAL GREASE WHICH EMITS CARBON DIOXIDE TO QUENCH THE FLAME AMOCO CORPORATION (US) 1990-02-27 US disclosed
US-4902435-A LUBRICANTS AMOCO CORPORATION (US) 1990-02-20 US disclosed
US-4830767-A MIXTURE OF BASE OIL, POLYUREA THICKENER, CARBONATE, PHOSPHATE; EXTREME PRESSURE, WEAR RESISTANCE AMOCO CORPORATION (US) 1989-05-16 US disclosed
EP-0296362-A2 Lubricating grease, process for its preparation and its use AMOCO CORPORATION (US) 1988-12-28 EP disclosed
US-4787992-A ADDITIVES OF THE GROUP 1 OR 2 METAL CARBONATES AND PHOSPHATES; EXTREME PRESSURE LUBRICANTS AMOCO CORPORATION (US) 1988-11-29 US disclosed
US-4759859-A Lubricant grease consists of urea thickener, a combined carbonate and phosphate additive package, a borate containing oil separation inhibitor AMOCO CORPORATION (US) 1988-07-26 US disclosed
EP-0233757-A2 Front-wheel drive grease AMOCO CORPORATION (US) 1987-08-26 EP disclosed
US-3983041-A ALKALINE EARTH CARBONATE OR CARBOXYLATE, ALKYLPHENOL-FORMALDEHYDE-AMINE MANNICH BASE CHEVRON RESEARCH COMPANY (US) 1976-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12010990-B2 Hydrophobic polymers as oil rheology modifiers for agrochemical formulations DDT, NAPEPLD, LIPA ACHE 89/4885TEAD4 4318/4885MAPT 276/4885
US-20200288704-A1 HYDROPHOBIC POLYMERS AS OIL RHEOLOGY MODIFIERS FOR AGROCHEMICAL FORMULATIONS DDT, NAPEPLD, LIPA ACHE 89/4885TEAD4 4318/4885MAPT 276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.