Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224698 | 0.82 | TSHR (0.49) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL9227186 | 0.81 | TSHR (0.47) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL5057431 | 0.80 | TSHR (0.58) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL29207409 | 0.79 | LTA4H (0.56) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL7056375 | 0.78 | RARB (0.50) | CNR2PTPN11GPR3PDK2MCL1 | |
| SCHEMBL4605914 | 0.78 | PPARA (0.51) | PPARAPPARGCNR1CNR2PTPN11 | |
| SCHEMBL7735955 | 0.77 | RARB (0.53) | CNR2PTPN11MCL1RARB | |
| SCHEMBL9226161 | 0.77 | CYP1A2 (0.50) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL7061692 | 0.76 | RARB (0.46) | PTPN11GPR3PDK2FAAHPLA2G4B | |
| SCHEMBL17509796 | 0.76 | PPARA (0.68) | TSHRPPARAPPARGCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144546-A3 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2002-08-28 | — | — | EP | disclosed |
| EP-1144546-A2 | FLUORINATED TERPHENYLS | QinetiQ Limited (GB) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000004111-A2 | FLUORINATED TERPHENYLS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2000-01-27 | — | — | WO | disclosed |