Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.41 |
| ▸ | ITGAV | P06756 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788773 | 0.91 | ITGB3 (0.42) | LMNAL3MBTL1ITGB3ITGAVCA1 | |
| SCHEMBL7788750 | 0.90 | ITGB3 (0.41) | LMNAL3MBTL1HTTITGB3ITGAV | |
| SCHEMBL7785677 | 0.86 | ITGB3 (0.51) | LMNAL3MBTL1ALOX15TSHRHTT | |
| SCHEMBL7785678 | 0.86 | ITGB3 (0.51) | LMNAL3MBTL1ALOX15TSHRHTT | |
| SCHEMBL13715863 | 0.84 | PKM (0.46) | LMNAL3MBTL1ITGB3ITGAVCA1 | |
| SCHEMBL7194908 | 0.83 | ITGB3 (0.51) | LMNAITGB3ITGAVPKMF2 | |
| SCHEMBL7789975 | 0.82 | ITGB3 (0.46) | LMNAHTTITGB3ITGAVPKM | |
| SCHEMBL7191727 | 0.82 | ITGB3 (0.46) | L3MBTL1ITGB3ITGAVCA1CA2 | |
| SCHEMBL7788313 | 0.81 | ITGB3 (0.45) | LMNAHTTITGB3ITGAVCA1 | |
| SCHEMBL7785662 | 0.81 | MAPT (0.48) | LMNAHTTITGB3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |