Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789857 | 0.85 | NR1H4 (0.51) | MAPTSMN1; SMN2NPC1HTTMEN1 | |
| SCHEMBL7789813 | 0.81 | CYP1A2 (0.59) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9268448 | 0.80 | NPC1 (0.71) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7791330 | 0.77 | RAB9A (0.62) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28152490 | 0.76 | ALOX5 (0.67) | POLBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1003761 | 0.75 | KDM4E (0.62) | POLBKDM4EALDH1A1PLAUNPC1 | |
| SCHEMBL2355805 | 0.74 | PLAU (0.56) | POLBKDM4EALDH1A1PLAUHPGD | |
| SCHEMBL30929964 | 0.73 | MAPT (0.49) | POLBKDM4EALDH1A1PLAUMAPT | |
| Hydrochloric Acid SCHEMBL15414839 | 0.73 | KDM4E (0.60) | POLBKDM4EALDH1A1PLAUNPC1 | |
| SCHEMBL1123058 | 0.72 | MAPT (0.62) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |