Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7780969 | 0.94 | CAPN1 (0.43) | OPRM1OPRK1APLNRIL23RCAPN1 | |
| SCHEMBL8896882 | 0.91 | OPRM1 (0.47) | OPRM1OPRK1EPHA2APLNR | |
| SCHEMBL7785528 | 0.90 | OPRM1 (0.45) | OPRM1OPRK1EPHA2APLNRCAPN1 | |
| SCHEMBL7785514 | 0.88 | EPHA2 (0.46) | OPRM1OPRK1EPHA2APLNR | |
| SCHEMBL29871917 | 0.86 | OPRM1 (0.46) | OPRM1OPRK1EPHA2AKT1 | |
| SCHEMBL10435105 | 0.83 | EPHA2 (0.51) | OPRM1OPRK1EPHA2 | |
| SCHEMBL29391116 | 0.82 | EPHA2 (0.45) | OPRM1OPRK1EPHA2 | |
| SCHEMBL29630472 | 0.82 | XIAP (0.45) | OPRM1OPRK1EPHA2 | |
| SCHEMBL7789924 | 0.82 | OPRM1 (0.48) | OPRM1OPRK1EPHA2 | |
| SCHEMBL10434942 | 0.81 | OPRM1 (0.46) | OPRM1OPRK1EPHA2IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | claimed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | claimed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | claimed |
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | disclosed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | disclosed |