Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.45 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.41 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.41 |
| ▸ | RAMP3 | O60896 | 2/20 | 0.40 |
| ▸ | CALCR | P30988 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785514 | 0.92 | EPHA2 (0.46) | OPRM1OPRK1EPHA2CXCR4APLNR | |
| SCHEMBL8896882 | 0.92 | OPRM1 (0.47) | OPRM1OPRK1EPHA2CXCR4APLNR | |
| SCHEMBL7789919 | 0.90 | OPRM1 (0.43) | OPRM1OPRK1EPHA2CAPN1APLNR | |
| SCHEMBL7780969 | 0.90 | CAPN1 (0.43) | OPRM1OPRK1CAPN1APLNRRAMP3 | |
| SCHEMBL7789924 | 0.84 | OPRM1 (0.48) | OPRM1OPRK1EPHA2CXCR4NMUR2 | |
| SCHEMBL30185759 | 0.84 | APLNR (0.48) | OPRM1OPRK1EPHA2APLNRNMUR2 | |
| SCHEMBL22300346 | 0.82 | OPRM1 (0.51) | OPRM1OPRK1CAPN1APLNRNMUR2 | |
| SCHEMBL7786086 | 0.82 | OPRM1 (0.45) | OPRM1OPRK1EPHA2CXCR4APLNR | |
| SCHEMBL29451974 | 0.82 | OPRM1 (0.52) | OPRM1OPRK1APLNR | |
| SCHEMBL7788531 | 0.82 | CXCR4 (0.45) | OPRM1EPHA2CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | claimed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | claimed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | claimed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | claimed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | claimed |
| EP-0723454-B1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | GOLDSTEIN GIDEON (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0723454-A4 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RES INST INC (US) | 1998-07-29 | — | — | EP | disclosed |
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0723454-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | Goldstein, Gideon (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995005841-A1 | NOVEL TRIPEPTIDES USEFUL IN IMMUNE AND CNS THERAPY | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1995-03-02 | — | — | WO | disclosed |