Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 14/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 14/20 | 0.47 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785528 | 0.92 | OPRM1 (0.45) | OPRM1OPRK1APLNREPHA2CXCR4 | |
| SCHEMBL7789919 | 0.91 | OPRM1 (0.43) | OPRM1OPRK1APLNREPHA2 | |
| SCHEMBL7780969 | 0.91 | CAPN1 (0.43) | OPRM1OPRK1APLNR | |
| SCHEMBL7785514 | 0.90 | EPHA2 (0.46) | OPRM1OPRK1APLNREPHA2CXCR4 | |
| SCHEMBL7789924 | 0.83 | OPRM1 (0.48) | OPRM1OPRK1EPHA2CXCR4F2 | |
| SCHEMBL29571998 | 0.82 | OPRM1 (0.48) | OPRM1OPRK1APLNREPHA2 | |
| SCHEMBL29802094 | 0.82 | OPRM1 (0.45) | OPRM1OPRK1EPHA2F2 | |
| SCHEMBL22872708 | 0.81 | NRP1 (0.54) | OPRM1OPRK1EPHA2F2 | |
| SCHEMBL29451974 | 0.81 | OPRM1 (0.52) | OPRM1OPRK1APLNRF2 | |
| SCHEMBL22300346 | 0.81 | OPRM1 (0.51) | OPRM1OPRK1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639729-A | NERVOUS SYSTEM DISORDERS | IMMUNOBIOLOGY RESEARCH INSTITUTE, INC. (US) | 1997-06-17 | — | — | US | disclosed |