Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 11/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787026 | 0.85 | CAPN1 (0.51) | CAPN1NPC1RAB9ACTSB | |
| SCHEMBL7786982 | 0.85 | ROCK2 (0.50) | CTSLNPC1RAB9APLA2G10PLA2G2A | |
| SCHEMBL7313788 | 0.84 | CAPN1 (0.48) | CAPN1CTSLCTSBPTPN1 | |
| SCHEMBL7314900 | 0.84 | PYGL (0.43) | CAPN1NPC1RAB9ACTSBPLA2G10 | |
| SCHEMBL7787789 | 0.80 | CAPN1 (0.48) | CAPN1CTSB | |
| SCHEMBL28227062 | 0.79 | PLA2G10 (0.46) | PLA2G10PLA2G2A | |
| SCHEMBL7782229 | 0.78 | CAPN1 (0.51) | CAPN1CTSB | |
| SCHEMBL7791341 | 0.78 | CAPN1 (0.61) | CAPN1CTSB | |
| SCHEMBL7787794 | 0.78 | CAPN1 (0.53) | CAPN1CTSB | |
| SCHEMBL7322246 | 0.78 | TSHR (0.50) | PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |