Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785607 | 0.93 | LMNA (0.46) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL7194899 | 0.91 | ITGB3 (0.44) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL7789969 | 0.91 | CYP26A1 (0.42) | LMNAMAPTSMN1; SMN2CTSAITGB3 | |
| SCHEMBL7781206 | 0.90 | ITGB3 (0.42) | MAPTKMT2AMEN1CTSAITGB3 | |
| SCHEMBL7788355 | 0.89 | MMP12 (0.47) | LMNASMN1; SMN2ITGB3ITGAVF10 | |
| SCHEMBL7790178 | 0.89 | CTSA (0.41) | MAPTKMT2AMEN1CTSAITGB3 | |
| SCHEMBL7788749 | 0.88 | ITGB3 (0.44) | LMNAMAPTKMT2AMEN1CYP3A4 | |
| SCHEMBL7790163 | 0.87 | ALDH1A1 (0.46) | KMT2AMEN1CYP3A4CYP2C19ITGB3 | |
| SCHEMBL7781180 | 0.87 | EEF2K (0.46) | CTSAITGB3F10ITGA2B | |
| SCHEMBL7790073 | 0.86 | CYP26A1 (0.46) | LMNAMAPTKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |