Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785658 | 0.93 | LMNA (0.44) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7194899 | 0.91 | ITGB3 (0.44) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7790073 | 0.90 | CYP26A1 (0.46) | LMNAMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7788749 | 0.88 | ITGB3 (0.44) | LMNAMAPTMEN1KMT2ACYP3A4 | |
| SCHEMBL7786241 | 0.88 | CTSA (0.46) | MEN1KMT2AS1PR3GPR139ALDH1A1 | |
| SCHEMBL7789969 | 0.87 | CYP26A1 (0.42) | LMNAMAPTSMN1; SMN2ALDH1A1ITGB3 | |
| SCHEMBL7781206 | 0.86 | ITGB3 (0.42) | MAPTMEN1KMT2AMAPK1ITGB3 | |
| SCHEMBL7786214 | 0.85 | S1PR3 (0.41) | MEN1KMT2ACYP2C9CYP2C19S1PR3 | |
| SCHEMBL7790178 | 0.85 | CTSA (0.41) | MAPTMEN1KMT2AMAPK1ITGB3 | |
| SCHEMBL7788355 | 0.84 | MMP12 (0.47) | LMNASMN1; SMN2KAT6AITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147079-A2 | BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000041469-A2 | β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-20 | — | — | WO | disclosed |