Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 5/20 | 0.51 |
| ▸ | MMP2 | P08253 | 5/20 | 0.51 |
| ▸ | MMP8 | P22894 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784734 | 0.80 | KMT2A (0.45) | FDFT1KMT2AMEN1KDM4EMAPT | |
| SCHEMBL7790656 | 0.77 | FDFT1 (0.68) | FDFT1CA12MMP2MMP8CA1 | |
| SCHEMBL5100534 | 0.76 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL7794868 | 0.76 | FDFT1 (0.66) | FDFT1CA12MMP2MMP8CA1 | |
| SCHEMBL17187151 | 0.73 | MMP2 (0.83) | FDFT1CA12MMP2MMP8CA1 | |
| SCHEMBL30556990 | 0.72 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL8184735 | 0.72 | KMT2A (0.51) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL26120465 | 0.72 | KMT2A (0.51) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL29636514 | 0.72 | KMT2A (0.55) | KMT2AMEN1KDM4EMAPTALDH1A1 | |
| SCHEMBL31129249 | 0.70 | KMT2A (0.67) | KMT2AMEN1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |