Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410675 | 0.82 | FFAR1 (0.46) | KMT2AMEN1KDM4EPABPC1POLB | |
| SCHEMBL7793613 | 0.82 | L3MBTL1 (0.45) | KMT2AMEN1KDM4EMAPTFDFT1 | |
| SCHEMBL7793634 | 0.82 | FDFT1 (0.42) | KDM4EMAPTFDFT1POLBLMNA | |
| SCHEMBL7790660 | 0.80 | FDFT1 (0.65) | KMT2AMEN1KDM4EMAPTPABPC1 | |
| SCHEMBL5366533 | 0.74 | FDPS (0.59) | MAPTRAB9ANPC1ALDH1A1POLB | |
| SCHEMBL7793582 | 0.73 | KDM4E (0.43) | KMT2AMEN1KDM4EMAPTPOLB | |
| SCHEMBL5363659 | 0.73 | RAB9A (0.49) | KMT2AKDM4EMAPTRAB9ANPC1 | |
| SCHEMBL7793579 | 0.72 | KDM4E (0.43) | KMT2AKDM4ERAB9ANPC1FDFT1 | |
| SCHEMBL5100534 | 0.72 | KMT2A (0.49) | KMT2AMEN1KDM4EMAPTPABPC1 | |
| SCHEMBL8349276 | 0.69 | KMT2A (0.53) | KMT2AMEN1KDM4EMAPTPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | claimed |
| EP-0762883-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1997-03-19 | — | — | EP | claimed |
| WO-1995033466-A1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 1995-12-14 | — | — | WO | claimed |
| EP-0762883-B1 | PYRIDYLBISPHOSPHONATES FOR USE AS A THERAPEUTICAL AGENT | LEIRAS OY (FI) | 2001-11-14 | — | — | EP | disclosed |
| US-5866556-A | BONE DISORDERS | LEIRAS OY (FI) | 1999-02-02 | — | — | US | disclosed |