SCHEMBL7790685

SCHEMBL7790685

Clc1cccc2c1[CH]C=C2

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7793769 0.81 CYP1A2 (0.36) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL218296 0.71 CYP2A6 (0.36) CYP1A2CYP2A6TSHRALDH1A1
SCHEMBL7793683 0.71 CES2 (0.31)
SCHEMBL7784987 0.71
SCHEMBL27311536 0.70 CYP1A2 (0.31) CYP1A2CYP2A6ALDH1A1
SCHEMBL6537045 0.70 ALDH1A1 (0.30) CYP2A6ALDH1A1
SCHEMBL4622985 0.69 CYP1A2 (0.30) CYP1A2CYP2A6
SCHEMBL27340902 0.68 ACHE (0.31)
SCHEMBL5082813 0.67 ALDH1A1 (0.37) CYP2A6ALDH1A1TDP1
SCHEMBL7794612 0.67 ALDH1A1 (0.35) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed