SCHEMBL7793769

SCHEMBL7793769

Clc1cccc2c1C=C[CH]2

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790685 0.81 CYP1A2 (0.36) CYP1A2CYP2A6TSHRLMNAALDH1A1
SCHEMBL26202 0.71 CYP2A6 (0.36) CYP1A2CYP2A6TSHRALDH1A1
SCHEMBL7794334 0.71 CES2 (0.31)
SCHEMBL28031409 0.71 PTGS2 (0.40) CYP1A2TSHRALDH1A1MEN1KMT2A
SCHEMBL27324211 0.70 CYP1A2 (0.31) CYP1A2CYP2A6ALDH1A1
SCHEMBL7773543 0.70 CYP2A6 (0.35) CYP1A2CYP2A6TSHRALDH1A1
SCHEMBL6537049 0.70 ALDH1A1 (0.30) CYP2A6ALDH1A1
SCHEMBL4622985 0.69 CYP1A2 (0.30) CYP1A2CYP2A6
SCHEMBL28135294 0.68
SCHEMBL26190 0.67 ALDH1A1 (0.37) CYP2A6ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633471-B2 Ethylene-based polymer, polyethylene-based resin composition and use thereof, catalyst component for olefin polymerization, olefin polymerization catalyst containing the component, and method for producing ethylene-based polymer by using the catalyst JAPAN POLYETHYLENE CORPORATION (JP) 2020-04-28 US disclosed
US-20180237565-A1 ETHYLENE-BASED POLYMER, POLYETHYLENE-BASED RESIN COMPOSITION AND USE THEREOF, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, OLEFIN POLYMERIZATION CATALYST CONTAINING THE COMPONENT, AND METHOD FOR PRODUCING ETHYLENE-BASED POLYMER BY USING THE CATALYST JAPAN POLYETHYLENE CORPORATION (JP) 2018-08-23 US disclosed
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed