SCHEMBL7790871

SCHEMBL7790871

C=Cc1cccc2c1C=[C]C2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
MIF P14174 1/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790734 0.69 ADRA2A (0.32) DRD2
SCHEMBL7793785 0.69 ALDH1A1 (0.33) ALDH1A1
SCHEMBL586150 0.67 ALDH1A1 (0.34) ALDH1A1DRD2
SCHEMBL7636146 0.67 ALDH1A1 (0.34) ALDH1A1DRD2
SCHEMBL7816533 0.64 TSHR (0.33) ALDH1A1DRD2
SCHEMBL7790916 0.63 ALDH1A1 (0.45) ALDH1A1DRD2
SCHEMBL10692880 0.63 ALDH1A1 (0.48) ALDH1A1MIFDRD2
SCHEMBL4595232 0.63 ALDH1A1 (0.38) ALDH1A1DRD2
SCHEMBL4962062 0.62 ALDH1A1 (0.46) ALDH1A1
SCHEMBL6055372 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed