SCHEMBL7790734

SCHEMBL7790734

Fc1cccc2c1C=[C]C2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.32
DRD2 P14416 1/20 0.32
DRD3 P35462 1/20 0.32
HTR5A P47898 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7790871 0.69 ALDH1A1 (0.33) DRD2
SCHEMBL4163215 0.65 HTR5A (0.39) HTR5A
SCHEMBL20509567 0.62 DRD2 (0.36) ADRA2ADRD2DRD3HTR5A
SCHEMBL9956581 0.61 HTR5A (0.38) ADRA2ADRD2DRD3HTR5A
SCHEMBL3511272 0.61 TSHR (0.43)
SCHEMBL20528826 0.61 TRPA1 (0.34)
SCHEMBL9377898 0.61
SCHEMBL25079074 0.60 DRD2 (0.34) ADRA2ADRD2DRD3HTR5A
SCHEMBL19926250 0.60 TSHR (0.37) ADRA2ADRD2DRD3HTR5A
SCHEMBL4311507 0.60 DRD2 (0.31) DRD2DRD3HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155698-A1 ORGANOBORON COMPOUNDS EXHIBITING ANTICOCCIDIAL ACTIVITIES Nitto Kasei Co., Ltd. (JP) 2001-11-21 EP disclosed