Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7791245 | 1.00 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL7783428 | 0.82 | NFE2L2 (0.53) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL7783430 | 0.82 | NFE2L2 (0.53) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL7793263 | 0.81 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL7793268 | 0.81 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL7788578 | 0.81 | TRPA1 (0.40) | NPC1RAB9ATRPA1CYP1A2CYP3A4 | |
| SCHEMBL7789174 | 0.81 | CHRM5 (0.42) | TRPA1CYP1A2CHRM5TUBB1GAA | |
| SCHEMBL7789175 | 0.81 | CHRM5 (0.42) | TRPA1CYP1A2CHRM5TUBB1GAA | |
| SCHEMBL7788581 | 0.81 | TRPA1 (0.40) | NPC1RAB9ATRPA1CYP1A2CYP3A4 | |
| SCHEMBL7789229 | 0.80 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825176-B1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK & CHEMICALS (JP) | 2001-11-14 | — | — | EP | disclosed |
| EP-0825176-A1 | Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1998-02-25 | — | — | EP | disclosed |