Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7797652 | 0.88 | L3MBTL1 (0.46) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7797647 | 0.87 | ALDH1A1 (0.46) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL7797559 | 0.87 | ALDH1A1 (0.38) | CNR2LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL7797580 | 0.85 | ERCC5 (0.43) | LMNAALDH1A1KMT2AMEN1ABCB11 | |
| SCHEMBL7791495 | 0.84 | NPC1 (0.46) | LMNAALDH1A1KMT2AMEN1POLB | |
| SCHEMBL9178311 | 0.83 | L3MBTL1 (0.46) | LMNAALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8656066 | 0.82 | ALDH1A1 (0.46) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7802020 | 0.81 | MEN1 (0.46) | LMNAALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8654757 | 0.80 | ERCC5 (0.43) | LMNAALDH1A1KMT2AMEN1ABCB11 | |
| SCHEMBL7799547 | 0.80 | SMN1; SMN2 (0.45) | LMNAALDH1A1KMT2AMEN1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010008947-A1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES | VARASI MARIO (IT) | 2001-07-19 | — | — | US | disclosed |
| EP-0662948-B1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES WITH KYNURENINASE AND/OR KYNURENINE-3-HYDROXYLASE INHIBITING ACTIVITY | PHARMACIA & UPJOHN SPA (IT) | 1998-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010008947-A1 | 2-AMINO-4-PHENYL-4-OXO-BUTYRIC ACID DERIVATIVES | KYNU, KMO, ABAT | CNR2 742/4885LMNA 3836/4885FLT1 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.