SCHEMBL7792167

SCHEMBL7792167

CCc1cc(CC(=O)O)cc(C2(C)CCCCC2)c1OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR Q13258 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.43
RARB P10826 3/20 0.37
RARG P13631 3/20 0.37
RARA P10276 2/20 0.37
THRB P10828 7/20 0.37
THRA P10827 6/20 0.36
GAA P10253 2/20 0.34
TSHR P16473 2/20 0.34
PTGS1 P23219 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34
ALDH1A1 P00352 1/20 0.34
NFKB1 P19838 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP26A1 O43174 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7796429 0.88 CYP26B1 (0.41) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7794887 0.86 PTGDR (0.43) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8400745 0.83 KMT2A (0.40) PTGDRPTGDR2RARBRARGRARA
SCHEMBL6568848 0.83 RARB (0.36) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7940089 0.83 TSHR (0.46) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7940452 0.82 PTGDR (0.41) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7786557 0.82 RARB (0.47) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7944733 0.81 TNKS2 (0.37) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8400776 0.78 ALOX5 (0.43) PTGDRPTGDR2RARBRARGRARA
SCHEMBL8400766 0.78 PTGDR (0.36) PTGDRPTGDR2RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed