SCHEMBL7796429

SCHEMBL7796429

CCc1cc(CCC(=O)O)cc(C2(C)CCCCC2)c1OC

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP26B1 Q9NR63 4/20 0.41
CYP26A1 O43174 3/20 0.41
PTGDR Q13258 1/20 0.39
PTGDR2 Q9Y5Y4 1/20 0.39
RARB P10826 3/20 0.38
RARG P13631 3/20 0.38
RARA P10276 2/20 0.38
THRA P10827 6/20 0.38
THRB P10828 6/20 0.38
CYP3A4 P08684 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RXRA P19793 1/20 0.34
FFAR1 O14842 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792167 0.88 PTGDR (0.43) CYP26A1PTGDRPTGDR2RARBRARG
SCHEMBL7794944 0.86 THRA (0.41) CYP26B1CYP26A1PTGDRPTGDR2RARB
SCHEMBL6568848 0.86 RARB (0.36) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7941069 0.84 ALDH1A1 (0.37) RARBRARGRARAALDH1A1
SCHEMBL7944733 0.84 TNKS2 (0.37) PTGDRPTGDR2RARBRARGRARA
SCHEMBL7941331 0.84 GLA (0.44) CYP26B1CYP26A1PTGDRPTGDR2RARB
SCHEMBL7942372 0.83 CYP26B1 (0.39) CYP26B1CYP26A1PTGDRPTGDR2RARB
SCHEMBL7786557 0.80 RARB (0.47) CYP26B1CYP26A1PTGDRPTGDR2RARB
SCHEMBL7796541 0.78 RARA (0.53) CYP26B1CYP26A1PTGDRPTGDR2RARB
SCHEMBL8400745 0.77 KMT2A (0.40) PTGDRPTGDR2RARBRARGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed