SCHEMBL7792495

SCHEMBL7792495

CCc1cc(CCC(=O)O)cc(C2CCCCC2)c1O

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.44
THRA P10827 2/20 0.44
FFAR1 O14842 3/20 0.39
FFAR4 Q5NUL3 2/20 0.39
PTGDR2 Q9Y5Y4 9/20 0.39
NUDT1 P36639 1/20 0.39
BACE1 P56817 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
S1PR5 Q9H228 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
PTGDR Q13258 3/20 0.35
PTGER2 P43116 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alcohol SCHEMBL28852088 0.89 THRB (0.46) THRBTHRAFFAR1FFAR4PTGDR2
SCHEMBL38822 0.89 THRB (0.50) THRBTHRAFFAR1FFAR4PTGDR2
Ammonia Solution, Strong SCHEMBL4052129 0.87 THRB (0.49) THRBTHRAFFAR1FFAR4PTGDR2
SCHEMBL7795915 0.86 THRB (0.46) THRBTHRAPTGDR2NUDT1BACE1
Ethylene SCHEMBL4047965 0.86 THRB (0.48) THRBTHRAFFAR1FFAR4PTGDR2
Octane SCHEMBL27811633 0.85 THRA (0.46) THRBTHRAFFAR1FFAR4PTGDR2
SCHEMBL7792116 0.85 THRA (0.45) THRBTHRAFFAR1FFAR4PTGDR2
SCHEMBL3814399 0.85 NUDT1 (0.41) PTGDR2NUDT1BACE1KDM4EMEN1
SCHEMBL7794938 0.83 THRA (0.47) THRBTHRAFFAR1FFAR4PTGDR2
SCHEMBL7944855 0.83 ALOX5 (0.40) THRBTHRAPTGDR2NUDT1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed